FDC2018 Speaker Preview

21st Century Laser-assisted Dentistry

By Dr. Anthony Cardoza

Over the last 29 years, I have witnessed many technological advances in dentistry. Some of these advances have included computers throughout the office, digital X-rays, digital intra-oral photography, loupe and microscope magnification, and CAD/CAM technology, just to name a few. One of the most significant technological advances has been the evolution of the dental laser, and it’s this technology that’s really firing my passion for dentistry.

Lasers have been used in dentistry for several decades, but during the last five years they have become widely accepted and now tens of thousands of dentists in the U.S. and around the world have implemented lasers. Market acceptance of dental lasers is rapidly growing at a level where digital imaging was five to seven years ago.

In my practice we have several lasers for both hard- and soft-tissue applications, which are used for a wide range of procedures. It’s well-established that different procedures require different laser wavelengths. Wavelength is important because specific body tissues (chromophores) interact in different ways depending on the laser source. Therefore, it’s important to use the proper wavelength that is tissue-specific for the procedure.

The following are a few of the laser procedures performed in our office every day and the clinical advantages they offer our practice and, most importantly, our patients.

The near infrared diode laser has become my laser of choice for hygiene and soft tissue. It’s extremely effective for hygiene procedures such as laser bacterial reduction (LBR) and laser de-epitheliazation during scaling and root planing. Additionally, it’s excellent for soft-tissue surgical procedures such as frenectomy, gingivectomy, fibroma removal, and gingival retraction for crown and bridge impressions.

The most versatile laser I have is the erbium mid-infrared wavelength hard/soft-tissue laser. I use this laser several times a day for no-shot, no-drill cavity preps. My patients love being able to avoid having shots and post-op numbness. This laser gives me the ability to quickly and effectively remove decay, and often these restorations weren’t scheduled, but discovered during hygiene examinations. We can complete these procedures in one appointment and avoid the inconvenience of rescheduling the patient. With my erbium laser I can perform these procedures fast and often without anesthesia.

In addition, by lengthening the pulse duration, I also can perform many soft-tissue and bone procedures. Procedures like apicoectomy, gingivectomy, osseous recontouring and laser periodontal surgery are examples of treatments performed with the erbium laser.

Finally, lasers are now being used during endodontic treatment in the form of laser activated irrigation to greatly reduce bacteria and debris found in the canals without a net thermal elevation within the canal. Lasers also are now being used for snore reduction. The role of lasers in dentistry is continuing to increase as we see ongoing research in both lasers and their use in various applications in dentistry. The decision is no longer whether to add a laser to your practice, it’s just a matter of which laser will best fulfill your needs.

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Cordoza Photo (3)

Cordoza Photo (2)

 

Dr. Cardoza will be speaking at the 2018 Florida Dental Convention in Orlando in June. On Thursday, June 21, “Dispelling the ‘CSI Effect’ Myth” will be at 9 a.m., and “Dentistry’s Role in the Mass Disaster Scenario, Child Abuse and Intimate Partner Violence Recognition,” will be at 2 p.m. later that same day. On Friday, June 22, his workshop, “21st Century Laser-assisted Dentistry” will be at 9 a.m. with a repeat of the workshop at 2 p.m. To register, go to floridadentalconvention.com.

 

FDC2018 Speaker Preview

Mandibular Osteomyelitis Associated to Candida Albicans in Marijuana and Heroin Abusers: Literature Review and Case Series

By Mikhail Daya, DMD*; Isabella Anderson, BS+; and, Jason Portnof, DMD, MD, FACS, FIDC**

Background: Osteomyelitis of the mandible is most commonly caused by bacterial infections and is rarely linked to fungal infections. Friedman et al. studied the relationship of multiple drugs, including marijuana, opioids, nicotine and alcohol, and its effect on the immune system. It’s important to consider potential risks and complications of patients who are immunocompromised and present a history of substance abuse. These complications include infections and osteomyelitis, which can be associated with multiple microorganisms, such as fungus. Candida albicans is commonly found in skin and mucosa of healthy individuals; however, it has been proven to cause disease in individuals who are immunocompromised.

Case Presentation: Two cases of mandibular osteomyelitis after routine dental extractions and a history of drug abuse, including heroin and marijuana, are presented in this case series. The patients were both male, ages included a 40-year-old (Patient A) and a 45-year-old (Patient B). Both patients underwent routine dental extractions performed by two different oral surgeons. Patient A underwent routine extraction of tooth No. 19 and Patient B had an extraction of erupted tooth No. 32. Due to recurrent infections and non-healing extraction sites, both patients were referred to the Department of Oral and Maxillofacial Surgery at Nova Southeastern University. Patients A and B underwent multiple courses of antibiotics as well as incision and drainage without resolution. Cultures of the infected sites were collected and analyzed for aerobes, anaerobes and fungus. In the final microbiology, both cases yielded positive results for Candida albicans.

Once the final microbiology yielded positive results for Candida albicans, Patient A was treated with irrigation and debridement, and Patient B underwent a right mandibular resection. Both patients also were treated in combination with antimicrobial therapy and fluconazole leading to complete resolution.

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Fig. 1: Patient A. – Initial presentation after extraction of tooth No. 19 (Note: penrose drain in left mandible).
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Fig. 2: Patient A. – Two-month follow-up, non-healing extraction site of tooth No. 19.
Fig. 3
Fig. 3: Patient B. – Non-healing extraction site of tooth No. 32, with radiolucent area affecting the inferior border and tooth No. 31.
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Fig. 4: Patient B. – Right mandibular resection due to chronic osteomyelitis, two-month follow-up with hardware in place, disease free.

 

Discussion: Osteomyelitis is defined as a progressive inflammatory condition of the bone and bone marrow.1,2 This rare condition can affect any bone, but is commonly seen in teeth bearing bones of the facial skeleton, due to direct access of microorganisms through infected teeth.5 In 2012, Slenker et al. studied 212 cases of Candida osteomyelitis. In this study, the most commonly affected sites were vertebrae and sternum. Interestingly, only six of them affected the facial skeleton.4

Infections of dental origin have been historically associated to bacterial microorganisms; however, in recent years there has been a trend in increasing infections associated to fungal pathogens.6 This increase in prevalence of Candida infections have been associated to contributing factors such as growth in population of immunosuppressed patients, invasive surgeries and overuse of broad-spectrum antibiotics.7

We show two cases of mandibular osteomyelitis after routine dental extraction in patients with a history of marijuana and heroin abuse as their only significant comorbidity. Friedman et al. demonstrated a correlation between marijuana and heroin abuse and a susceptibility to infections; this is due to the direct effect of these drugs over the immune response against pathogens.3 Marijuana is the common name given to Cannabis sativa; this plant has been widely used for recreational and medicinal purposes.3 Marijuana has been directly associated to increased susceptibility to infections because of its effect on immune cells, macrophages, lymphocytes and cytokines.9,10,11 On the other hand, heroin and other opioids have been linked to increase susceptibility to infection by direct exposure of pathogens through injections as well as their direct action in immune cells.12,13

Both cases presented here were treated with a combination of surgical debridement and fluconazole. The management of Candida osteomyelitis has not been well established due to the uncommon nature of this condition. Treatment recommendations for Candida osteomyelitis are based on case reports and case series. Amphotericin B (AmB) has been used widely in the past;14 however, more recent literature supports the use of fluconazole or echinocandin over AmB due to high toxicity rate.4,15,16 Recommendations of the Infectious Diseases Society of America include the use of different antifungal combinations and surgical debridement in selected cases.

Conclusion: Although mandibular osteomyelitis is most commonly caused by bacterial microorganisms, special attention must be given to patients with medical histories of immunosuppression and illicit drug use of cannabis and opiates. Patients who do not respond to broad-spectrum antibiotics might benefit from bacterial cultures, fungal cultures and sensitivity. In cases of positive fungal microorganisms, anti-fungal treatment with an antifungal agent such as oral fluconazole is indicated if fungal organisms are yielded in the culture.

 

*Oral and Maxillofacial Surgery Chief Resident at Nova Southeastern University, Broward Health Medical Center, Joe DiMaggio Children’s Hospital.
+Fourth-year Dental Student at Nova Southeastern University
**Oral and Maxillofacial Surgery Associate Professor and Craniofacial Director at Nova Southeastern University and Joe DiMaggio Children’s Hospital.

Dr. Portnof will be speaking at the 2018 Florida Dental Convention in Orlando in June. He is presenting his course, “Opioid Disorder in Dental Patients,” on Thursday, June 21 at 9:30 a.m. and 12:30 p.m. To register, go to floridadentalconvention.com.

 

References:

  1. Dym H, Zeidan J. Microbiology of Acute and Chronic Osteomyelitis and Antibiotic Treatment. Dent Clin North Am 2017; 61(2):271-282.
  2.  Kushner GM. Osteomyelitis and osteoradionecrosis. In: Miloro M, editor. Peterson’s principles of oral and maxillofacial surgery. Lewiston (ME): BC Decker; 2004. pp 300-324.
  3. Friedman H, Newton C, Klein TW. Microbial Infections, Immunomodulation, and Drugs of Abuse. Clin Microbiol Rev 2003; 16(2):209-219.
  4. Slenker AK, Keith SW, Horn DL. Two hundred and eleven cases of Candida osteomyelitis: 17 case reports and a review of the literature. Diagn Microbiol Infect Dis 2012; 73(1):89-93.
  5. Baur DA, Altay MA, Flores-Hidalgo A, Ort Y, Quereshy FA. Chronic osteomyelitis of the mandible: Diagnosis and management — an institution’s experience over 7 years. J Oral Maxillofac Surg 2015; 73(4):655-665.
  6. Sanz-Rodriguez C, Hernandez-Surmann F, Bueno AG, Goizueta C, Noguerado A. Candida and bacterial mandibular osteomyelitis in an AIDS patient. Eur J Clin Microbiol Infect Dis 1988; 17(7):531-532.
  7. Blumberg HM, Jarvis WR, Soucie JM, Edwards JE, Patterson JE, Pfaller MA, et al. Risk factors for candidal bloodstream infections in surgical intensive care unit patients: The NEMIS Prospective Multicenter Study. The National Epidemiology Mycosis Survey. Clin Infect Dis 2001; 33(2):177-186.
  8. Daya M, Mederos H, McClure S. Refractory Odontogenic Infection Associated to Candida Albicans: A Case Report. Clin Surg 2017; 2:1397.
  9. Baldwin GC, Tashkin DP, Buckley DM, Park AN, Dubinett SM, Roth MD. Marijuana and cocaine impair alveolar macrophage function and cytokine production. Am J Respir Crit Care Med 1997; 156(5):1606-1613.
  10. Derocq J, Segui M, Marchand J, LeFur G, Casellas P. Cannabinoids enhance human B-cell growth at low nanomolar concentrations. FEBS Lett 1995; 369:177-182.
  11. Srivastava MD, Srivastava BI, Brouhard B. Delta9 tetrahydrocannabinol and cannabidiol alter cytokine production by human immune cells. Immunopharmacology 1998; 40(3):179-185.
  12. Donahoe RM. Drug abuse and AIDS: causes for the connection. NIDA Res Monogr 1990; 96:181-191.
  13. McCarthy L, Wetzel M, Sliker JK, Eisenstein TK, Rogers TJ. Opioids, opioid receptors, and the immune response. Drug Alcohol Depend 2001; 62(2):111–123.
  14. Miller DJ, Mejicano GC. Vertebral osteomyelitis due to Candida species: case report and literature review. Clin Infect Dis 2001; 33(4):523-530.
  15. Neofytos D, Huprikar S, Reboli A, Schuster M, Azie N, Franks B, et al. Treatment and outcomes of Candida osteomyelitis: review of 53 cases from the PATH Alliance (R) registry. Eur J Clin Microbial Infect Dis 2014; 33(1):135-141.
  16. Mora-Duarte J, Betts R, Rotstein C, Colombo AL, Thompson-Moya L, Smietana J, et al. Comparison of caspofungin and amphotericin B for invasive candidiasis. N Engl J Med 2002; 347(25):2020-2029.
  17. Pappas P, Kauffman C, Andes D, Clancy C, Marr K, Ostrosky-Zeichner L, et al. Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America. Clin Infect Dis 2016; 62(4): e1-e50.

 

Come for the CE, Stay for the Fun at FDC2018!

The 2018 Florida Dental Convention (FDC) will be held June 21-23 at the Gaylord Palms Resort & Convention Center in Orlando. As a member benefit, Florida Dental Association (FDA) members can pre-register for FREE and earn up to 18 hours FREE continuing education (CE) credit.

This year’s theme, “Elevate Your Game,” is designed to assist the entire dental team with furthering their professional knowledge by offering more than 95 lectures and 30 workshops. FDC2018 has placed a conscious effort in specialty care CE, as well as focusing on complications that may arise during dental treatment.

Back by popular demand are “live dentistry” courses, designed for you to observe in-office operatory procedures firsthand. Course topics include orthodontic black triangles, CEREC and dental implant surgery.

Take advantage of free course tuition at FDC2018 and apply to be a speaker host. Lecture hosts will receive free course tuition for the hosted course and a lunch voucher for Exhibit Hall concessions. Workshop and certification hosts will receive free course tuition for an AM or PM lecture course of their choice and a lunch voucher for Exhibit Hall concessions. As a speaker host, you will introduce the speaker, make course announcements, pass out and collect surveys, and assist the speaker, if necessary. Click here to apply today!

Connect with more than 300 leading dental exhibitors at FDC2018. The Exhibit Hall will feature exhibitors ready to show you the latest technology, materials and instrumentation for your dental practice.

FDC offers fun for everyone! End each day with fun-filled and family-friendly events. On Thursday, sing along to Dueling Pianos, and on Friday, flashback in time at “80s Flashback!” If you are looking for nightlife, join the new dentists Friday night for “The After Party.”

Click here to register for FDC2018 today!

For questions or more information, email fdc@floridadental.org or call 850.681.3629.